NOT KNOWN FACTS ABOUT WHERE TO PHENOBARBITAL

Check Closely (one)phenobarbital will decrease the extent or outcome of fentanyl transmucosal by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Observe Intently. Coadministration of fentanyl with CYP3A4 inducers could lead to the decrease in fentanyl plasma concentrations, lack of efficacy or, maybe, improvement of the withdr